This is Project Report on HIV AIDS. Definition : Acquired Immuno Deficiency Syndrome. It is a pandemic disease. AIDS cannot be compared to disease like malaria and cholera which claim more live in country currently. It has a greater impact than other disease. The treatment options are still in the initial stages and are prohibitively expensive. There are instances of quacks taking advantage of the situation. This has compounded the misery of AIDS patients.
It was first noticed in USA in 1981. The American and French scientist independently identified the AIDS virus 1984. The virus first named as HCLV III ( Human cell leukemia virus III). The name (Human cell leukemia deficiency virus) is now preferred. It now seems that HIV first passed into human from chimpanzees by eating butchered chimps. 10% of the people, who get AIDS virus infection, actually develop full blown AIDS.
The main causes of AIDS is a disorder of cell mediated immune system of the body. The disorder is characterized by a reduction in the number of helper. T-cell which stimulate antibody production by B-cells. This result in the loss of natural defense against viral infection.
It is only transmitted by a direct contact of infected cells - containing blood of patient to the blood of a healthy person as in -
1) Sexual intercourse with an infected partner if there is tissue injury to permit blood contact.
2) Use of contaminated needles and syringes to inject drugs or vaccines.
3) Use of contaminated razors, needles for boring pinnae.
4) Transfusion of infected blood or blood product.
5) Organ transplant.
6) Artificial insemination.
7) Parturition from mother to baby due to rupturing of blood vessels.
Project on Other Diseases :
Note : The sexual of transmission account for over 75% of infections.AIDS is not a contagious disease. It does not spread by casual contact, such as handshake , body contact in crowded places, working or playing together , sharing clothes , eating food cooked by infected person, using same toilet, swimming pools. It is also not and ribovirin seem most promising. A drugs named zide vuidine prolongs the life of many AIDS patient. However some patients AIDS virus have already mutated to zidovudine resistant forms.
Introduction of aids virusIt is 100 to 140 nm. in diameter and has a cylindrical core. It is found in blood and semen and to a lesser extent in milk tears and saliva. It is a retrovirus, i.e. its genetic material is - RNA (single stranded linear) which can make a DNA copy of itself with the help of the reverse transcriptase enzyme. The virus bind specifically to a surface receptor on a helper T-cell and introduce its RNA and reverse transcriptase enzyme into the cells here it multiplies and the release of new virus destroys the cell. AIDS occurs when the helper T-cell falls too low to fight the disease.
Today ‘ELISA’ test is done identify this pandemic disease (AIDS).
i) Maligent tumours in connective tissue
ii) Viral, bacterial, protozoan and fungalin-fection of any system of the body. There are destruction of WBC’S, damage to brain,. unexplained fever, unexplained loss of appetite, unexplained loss weight over a short time, chronic diarrhea, cough, night sweats, enlargement of lymph glands, shortness of breath, weakness.AIDS Treatment :- Medical treatment of AIDS consist of :
i) Antiviral therapy against the causative agent
ii) Immuno simulative therapy to increase the number of resistance - providing cells in the body or both. However no specific treatment has been found so far and the mortality form AIDS is virtually 100%. A victim of full blown AIDS dies with in 3 year from infection of many drugs tried, azithmidine transmitted by blood sucking insects such as mosquitoes, AIDS virus has been found in urine, tears saliva, breast milk and vaginal secretions, but is seems not to transmitted by these fluids unless it gets a cut.Preventions from AIDS
Following steps may help in controlling this dreaded disease.
i) People particularly those in high risk group should be educated about AIDS transmission.
ii) High risk group should refrain from blood donation.
iii) Disposable needles and syringes should be used.
iv) Sexual habits should changed immediately.
v) Before receiving blood, ensure that it has been screened for HIV.
vi) Routine screening may be done in
a) Blood Donors,
b) Organ Donors
c) Donors of semen and growth hormone,
d) Patient receiving haemodialysis
e) Females in high risk group, Who are pregnant or contemplating pregnancy.
Chastity, life long monogamy, and a clean needle for each injection are the only ways to prevents the spread of AIDS. These measure will succeed only in persons not already infected.
Reasons of spreading AIDS among world people
More than 90% of the infected persons are belong to developing countries.
(i) Low-level of socio-economic development.
(ii) Low health consciousness and facilities
(iii) A growing unmarried youth population due to delayed marriage
(iv) High rate of labour migration.
(v) Low level of literacy among high-risk groups.
(vi)High incidence of sexuality transmitted diseases and reproductive tract infections among men and women.
(i) National AIDS programme of south East Asian countries are beginning to yield encouraging results. The 100% condom use programme in Thailand and the Sonagachi project in Calcutta, a model peer education programme among sex workers, have helped bring down AIDS infection and also reduced the incidence of STD.
(ii) Non-government organizations have brought Baptist interest litigations against such cases of discrimination and the courts have pronounced the rights of such peoples. This has helped alleviate the misery of affected persons.
ObservationAIDS immersed as pandemic disease. It is nondurable. It is more common in developing countries. Now every day 1000 peoples are going to become HIV infected in world. This is mainly due to blood transfusion & Sexual contact. In whole world about 3 crore 30 lakhs people are HIV +ve & in India 3 lakh 70 thousands are HIV +ve. The number of HIV +ve persons are higher in Tamilnadu Bombay, Calcutta and Kerala and Manipur. Problems for Patient AIDS cause disease of Immune system of body. The HIV cause damage to T & B cell. Thus this is becoming a threatening problem of today and of future.
AIDS is non curable due to its nature of pathogen. It also damage immune system of the body. Therefore any medicine (Antiviral) drugs are not effective against HIV virus. Ignorance and lack of knowledge about this disease is the root cause of wide spread of this disease.